Rarity of bacterial and viral meningitis in areas of Western Greece with fewer than 2,000 inhabitants.
نویسندگان
چکیده
The purpose of the present study was to compare the incidence of childhood meningitis in regions with fewer than 2,000 inhabitants (rural regions) and regions with more than 2,000 inhabitants (urban regions) in the prefecture of Achaia in Western Greece during 1991-2005. Included were all 555 children hospitalized for meningitis. The criteria for bacterial meningitis were (i) positive blood/cerebralspinal fluid (CSF) culture, Gram stain, or latex agglutination and/or (ii) increased beta-glucuronidase in CSF. In case of suspected bacterial meningitis, the following findings were considered: compatible clinical and laboratory findings, and whether or not a cure was achieved with antibiotic treatment and finally resulted in negative cultures. In cases of suspected viral meningitis, compatible clinical and laboratory findings were considered, together with observation of a cure without antibiotic treatment. Only 28 of 555 meningitis patients were from rural regions. The incidence per 10,000 children in rural and urban regions, respectively, was as follows: meningitis, 1.13 and 8.99; bacterial meningitis, 0.16 and 2.40; suspected bacterial meningitis, 0.52 and 3.00; and viral meningitis, 0.44 and 3.58. The incidence ratio for bacterial, suspected bacterial, and viral meningitis in urban versus rural regions was 14.85, 5.72, and 8.10, respectively. Only 2 of the 79 cases with a confirmed causative pathogen came from rural regions. In conclusion, compared to those living in urban regions, children living in rural regions are relatively spared from bacterial and viral meningitis.
منابع مشابه
Relative expression of fibroblast growth factor-1 in the cerebrospinal fluid of patients with bacterial meningitis; A Western Blot analysis
Meningitis is an inflammation of the membranes that surround the brain and spinal cord, thereby involving the arachnoid, the pia and the cerebrospinal fluid (CSF). It is divided into viral and bacterial meningitis. For different reasons the diagnosis of bacterial meningitis is very important. The examination of CSF samples may provide information about causative microorganism. The sensivity of ...
متن کاملارزش تشخیصی سطح سرمی پروکلسیتونین در افتراق مننژیت باکتریال از غیرباکتریال در کودکان یک ماهه تا 18 ساله مرکز طبی کودکان ، 83-1382
Background: Bacterial meningitis is a fatal disease with high mortality and morbidity that needs emergency management. But due to nonspecific signs and symptoms it;aposs diagnosis in children is difficult. Recently procalcitonin has been used for diagnosis of serious bacterial infections like bacterial meningitis. We conducted a prospective study in children for evaluation of procalcitonin in d...
متن کاملConcentration of soluble form of hepatocyte growth factor receptor in cerebrospinal fluid and serum of patients with bacterial and viral meningitis
Abstract Background and objectives: C-Met is a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR). The HGF receptor possesses tyrosine -kinase activity and it is essential for embryonic development, wound healing and cancer. Many proteins are proteolytically released from the surface by a process known as ectodomain shedding. Shedding occurs under normal phy...
متن کاملA Spinal Fluid Scoring System for Differentiation of Bacterial and Viral Meningitis
To develop such a system, a retrospective study was performed on patients with meningitis admitted at three major pediatric hospitals during a ten-year period. In this study, important cerebrospinal fluid ( CSF) indices were measured and compared in cases of bacterial and viral meningitis. Glucose, protein and white blood cells (WBCs) were analyzed in 609 patients with meningitis and scores wer...
متن کاملCommon Cause and Cerebrospinal Fluid Changes of Acute Bacterial Meningitis
Background and Objective: Bacterial meningitis is an important cause of mortality and long-term neural morbidity. Immediate diagnosis and treatment are necessary in appropriate time. This study was designed in Afzalipour Hospital in Kerman to evaluate meningitis causes, frequency and CSF laboratory changes. Patients and Methods: In this retrograde descriptive study from September 2003 to Se...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Japanese journal of infectious diseases
دوره 61 1 شماره
صفحات -
تاریخ انتشار 2008